Protection against yellow fever in monkeys by immunization with yellow fever virus nonstructural protein NS1

Inactivation of yellow fever virus by glutaraldehyde.

The preservation of cellular ultrastructure by glutaraldehyde is well documented (D. D. Sabatini et al., J. Cell Biol. 17:19, 1963); however, we could find no report of its inactivation of the yellow fever virus in tissue. As laboratory infection of unvaccinated personnel by this virus is also well known (G. P. Berry and S. F. Kitchen, Am. J. Trop. Med. 11:365, 1931), it is important to ascerta...

17D Yellow Fever Virus Vaccine

Dear Sir: In a recent article, Edupuganti and others reported a clinical study of co-administration of subcutaneous yellow fever (YF) 17D vaccine (YF-VAX Ò ; Sanofi Pasteur, Lyon, France) and intramuscular immune serum globulin (ISG) (amaSTAN S/D Ò ; Talecris Biotherapeutics, Research Triangle Park, NC) or saline placebo. 1 The study was designed to test whether co-administration of vaccine and...

Yellow fever virus/dengue-2 virus and yellow fever virus/dengue-4 virus chimeras: biological characterization, immunogenicity, and protection against dengue encephalitis in the mouse model.

Two yellow fever virus (YFV)/dengue virus chimeras which encode the prM and E proteins of either dengue virus serotype 2 (dengue-2 virus) or dengue-4 virus within the genome of the YFV 17D strain (YF5.2iv infectious clone) were constructed and characterized for their properties in cell culture and as experimental vaccines in mice. The prM and E proteins appeared to be properly processed and gly...

Yellow fever.

1MD, Infectious Disease Specialist, Hospital Israelita Albert Einstein, Sociedade Brasileira de Infectologia. MSc in Medicine – Infectious and Parasitic Diseases, Faculdade de Medicina da Universidade de São Paulo (FMUSP). PhD in Medicine – Infectious and Parasitic Diseases, FMUSP. Fellow American College of Physicians, São Paulo, SP, Brazil 2MD, Infectious Disease Specialist, Hospital Israelit...

Yellow fever